DECPA - Departamento de Clínicas Pediátrica e do Adulto
URI permanente desta comunidadehttp://www.hml.repositorio.ufop.br/handle/123456789/8505
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Item Diagnostic accuracy of the Berlin questionnaire and the NoSAS score in detecting risk for obstructive sleep apnea in rotating shift workers.(2021) Menezes Júnior, Luiz Antônio Alves de; Fajardo, Virgínia Capistrano; Nascimento Neto, Raimundo Marques do; Freitas, Silvia Nascimento de; Oliveira, Fernando Luiz Pereira de; Pimenta, Fausto Aloísio Pedrosa; Coelho, George Luiz Lins Machado; Meireles, Adriana LúciaBackground Data on the validity of tools for sleep apnea risk detection in rotating shift workers are limited. The aim was to evaluate the Berlin questionnaire (BQ) and the Neck, Obesity, Snoring, Age, Sex (NoSAS) score for the detection of obstructive sleep apnea risk in shift workers. Methods This cross-sectional study included male rotating shift workers, drivers of heavy of-road machinery in an iron ore extraction company. Polysomnography was the gold standard for evaluation. Obstructive sleep apnea (OSA) was defned as an apnea–hypopnea index (AHI) of≥5 events/h. The Shapiro–Wilk test verifed the data distribution and comparative analysis was conducted using the chi-square analyses and U Mann–Whitney with Bonferroni correction. Receiver operating characteristic curve analysis, sensitivity, specifcity, positive and negative predictive values, positive and negative likelihood ratios, and accuracy were used for evaluate BQ and NoSAS with OSA diagnosis by polysomnograph. Results Among 119 male shift workers, ages 24 to 57 years, polysomnography showed that 84% had obstructive sleep apnea (AHI≥5), and 46% had moderate to severe sleep apnea (AHI≥15). For AHI≥5, the NoSAS score had higher sensitivity and specifcity than the BQ. For AHI≥15 and AHI≥30, the NoSAS score had a sensitivity higher than 70% while BQ was 60% and 58%, respectively. The accuracy of the NoSAS score was higher for all OSA criteria than that of BQ. Conclusion In rotating shift workers, drivers of heavy of-road machinery, the NoSAS score showed higher accuracy in identifying patients at risk for sleep apnea than the BQ.Item Body fat indicators for cardiometabolic risk screening among shift workers.(2020) Diniz, Amanda Popolino; Alves, Márcia Elivane; Fajardo, Virgínia Capistrano; Freitas, Silvia Nascimento de; Batista, Guilherme Augusto Sousa; Athadeu, Bruno Francia Maia; Coelho, George Luiz Lins Machado; Oliveira, Fernando Luiz Pereira de; Pimenta, Fausto Aloísio Pedrosa; Nascimento Neto, Raimundo Marques doBackground: In view of the costly methods currently available for the assessment of body adiposity, anthropometric obesity indicators have proven effective in predicting cardiovascular risk. Objective: To investigate the discriminatory power of body fat indicators for cardiovascular risk screening among shift workers. Methods: Cross-sectional study with male employees of an iron ore extraction company. The predictive power of body fat indicators relative to cardiovascular risk was analyzed based on the Framingham risk score and metabolic syndrome by means of receiver operating characteristic curves, sensitivity, specificity, positive and negative predictive values, area under the receiver operating characteristic curve and Youden’s index. Results: The prevalence of cardiovascular risk was 14.2% in the metabolic syndrome risk model. According to the Framingham score, 95.0%, 4.1% and 0.9% of the participants exhibited low, moderate and high risk, respectively. All the analyzed body fat indicators exhibited satisfactory discriminatory power for the tested cardiovascular risk models. Conclusion: Waist-height ratio exhibited the highest ability to predict cardiometabolic risk in both risk models.Item Adiposity indicators as a screening method for polysomnography in shift workers.(2019) Diniz, Amanda Popolino; Fajardo, Virgínia Capistrano; Freitas, Silvia Nascimento de; Oliveira, Fernando Luiz Pereira de; Nascimento Neto, Raimundo Marques do; Pimenta, Fausto Aloísio Pedrosa; Coelho, George Luiz Lins MachadoObjective: to verify the discriminatory power of adiposity indicators in the prediction of obstructive sleep apnoea (OSA) in shift workers. Methods: a crosssectional study carried out in an iron ore extraction company, in Minas Gerais, Brazil. Anthropometric data were collected and polysomnography (PSG) was performed in 118 male shift workers who owned at least one overall risk factor for cardiovascular disease. Results: the OSA prevalence in the sample was 84.7%. Among the adiposity indicators used to predict OSA (≥ 5 events/hour), body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHtR), and total body fat (TBF) showed sensitivity values higher than 70%. Visceral fat (VF), neck circumference (NC), and neck-to-height ratio (NHtR) were the most effective in correctly identifying workers without OSA (specificity values higher than 70%). The areas under the receiver operating characteristic (ROC) curves for WC and NHtR were greater than 0.7, which indicated the test was effective in discriminating individuals with OSA. Conclusions: alterations in abdomen and neck adiposity indicators have a significant relationship with the presence of OSA and showed effectiveness as a screening method for PSG. WC and NHtR are considered good indicators for OSA prediction.Item A comparative study of methods for diagnosis of obesity in an urban mixed-race population in Minas Gerais, Brazil.(2007) Freitas, Silvia Nascimento de; Caiaffa, Waleska Teixeira; César, Cibele Comini; Cândido, Ana Paula Carlos; Faria, Valéria Andrade; Nascimento Neto, Raimundo Marques do; Coelho, George Luiz Lins MachadoObesity is defined as an excess of total body fat and may be assessed by different methods. The objective of the present study was to establish the discriminatory power of anthropometric data in determining obesity.Item Ability of body mass index to predict abnormal waist circumference : receiving operating characteristics analysis.(2013) Lauria, Márcio Weissheimer; Moreira, Lívia Maria Pinheiro; Coelho, George Luiz Lins Machado; Nascimento Neto, Raimundo Marques do; Soares, Maria Marta Sarquis; Ramos, Adauto VersianiBody mass index (BMI) and waist circumference (WC) are the most used anthropometric measures to identify obesity. While BMI is considered to be a simple and accurate estimate of general adiposity, WC is an alternative surrogate measure of visceral obesity. However, WC is subject to significant inter-examiner variation. The aim of the present study was to correlate BMI and WC measures in a group of Brazilian adults to determine the most accurate BMI values for predicting abnormal WC.Item Argyrophil cell density in the oxyntic mucosa is higher in female than in male morbidly obese patients.(2013) Maksud, Fabiana Alves Nunes; Kakehasi, Adriana Maria; Barbosa, Alfredo José AfonsoObesity is a multifactorial disorder often associated with many important diseases such as diabetes, hypertension and other metabolic syndrome conditions. Argyrophil cells represent almost the total population of endocrine cells of the human gastric mucosa and some reports have described changes of specific types of these cells in patients with obesity and metabolic syndrome. The present study was designed to evaluate the global population of argyrophil cells of the gastric mucosa of morbidly obese and dyspeptic non-obese patients. Gastric biopsies of antropyloric and oxyntic mucosa were obtained from 50 morbidly obese patients (BMI .40) and 50 non-obese patients (17 dyspeptic overweight and 33 lean individuals) and processed for histology and Grimelius staining for argyrophil cell demonstration. Argyrophil cell density in the oxyntic mucosa of morbidly obese patients was higher in female (238.68 ± 83.71 cells/mm2) than in male patients (179.31 ± 85.96 cells/mm2) and also higher in female (214.20 ± 50.38 cells/mm2) than in male (141.90 ± 61.22 cells/mm2) morbidly obese patients with metabolic syndrome (P = 0.01 and P = 0.02, respectively). In antropyloric mucosa, the main difference in argyrophil cell density was observed between female morbidly obese patients with (167.00 ± 69.30 cells/mm2) and without (234.00 ± 69.54 cells/mm2) metabolic syndrome (P = 0.001). In conclusion, the present results show that the number of gastric argyrophil cells could be under gender influence in patients with morbid obesity. In addition, gastric argyrophil cells seem to behave differently among female morbidly obese patients with and without metabolic syndrome.