Rapid antigen test as a tool for the identification of SARS-CoV-2 infection and its potential as a self-testing device.
dc.contributor.author | Filgueiras, Priscilla Soares | |
dc.contributor.author | Corsini, Camila Amormino | |
dc.contributor.author | Almeida, Nathalie Bonatti Franco | |
dc.contributor.author | Pedrosa, Maria Luysa Camargos | |
dc.contributor.author | Miranda, Daniel Alvim Pena de | |
dc.contributor.author | Gomes, Sarah Vieira Contin | |
dc.contributor.author | Assis, Jéssica Vieira de | |
dc.contributor.author | Silva, Raphael Antônio | |
dc.contributor.author | Medeiros, Maria Izabella Vieira de Assis Rocha Carvalho de | |
dc.contributor.author | Lourenço, Adelina Junia | |
dc.contributor.author | Bicalho, Cecilia Maria Florencio | |
dc.contributor.author | Vilela, Raquel Virgínia Rocha | |
dc.contributor.author | Jeremias, Wander de Jesus | |
dc.contributor.author | Fernandes, Gabriel da Rocha | |
dc.contributor.author | Grenfell, Rafaella Fortini Queiroz | |
dc.date.accessioned | 2023-10-20T19:23:13Z | |
dc.date.available | 2023-10-20T19:23:13Z | |
dc.date.issued | 2023 | pt_BR |
dc.description.abstract | Background: SARS-CoV-2 virus originated in Wuhan (China) in December (2019) and quickly spread worldwide. Antigen tests are rapid diagnostic tests (RDT) that produce results in 15-30 min and are an important tool for the scale-up of COVID-19 testing. COVID-19 diagnostic tests are authorized for self-testing at home in some countries, including Brazil. Widespread COVID-19 diagnostic testing is required to guide public health policies and control the speed of transmission and economic recovery. Methods: Patients with suspected COVID-19 were recruited at the Hospital da Baleia (Belo Horizonte, Brazil). The SARS-CoV-2 antigen- detecting rapid diagnostic tests were evaluated from June 2020 to June 2021 using saliva, nasal, and nasopharyngeal swab samples from 609 patients. Patient samples were simultaneously tested using a molecular assay (RT-qPCR). Sensitivity, specificity, accuracy, and positive and negative predictive values were determined using the statistical program, MedCalc, and GraphPad Prism 8.0. Results: The antigen-detecting rapid diagnostic tests displayed 98% specificity, 60% sensitivity, 96% positive predictive value, and moderate concordance with RT-qPCR. Substantial agreement was found between the two methods for patients tested < 7 days of symptom onset. Conclusions: Our findings support the use of Ag-RDT as a valuable and safe diagnostic method. Ag-RDT was also demonstrated to be an important triage tool for suspected COVID-19 patients in emergencies. Overall, Ag-RDT is an effective strategy for reducing the spread of SARS-CoV-2 and contributing to COVID-19 control. | pt_BR |
dc.identifier.citation | FILGUEIRAS, P. S. et al. Rapid antigen test as a tool for the identification of SARS-CoV-2 infection and its potential as a self-testing device. Revista da Sociedade Brasileira de Medicina Tropical, v. 56, artigo e0167, 2023. Disponível em: <https://www.scielo.br/j/rsbmt/a/TyFVt3tgWVdztfdrRXKyykG/>. Acesso em: 01 ago. 2023. | pt_BR |
dc.identifier.doi | https://doi.org/10.1590/0037-8682-0167-2022 | pt_BR |
dc.identifier.issn | 1678-9849 | |
dc.identifier.uri | http://www.repositorio.ufop.br/jspui/handle/123456789/17628 | |
dc.language.iso | en_US | pt_BR |
dc.rights | aberto | pt_BR |
dc.rights.license | This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/). Fonte: PDF do artigo. | pt_BR |
dc.subject | Covid-19 | pt_BR |
dc.subject | Rapid test | pt_BR |
dc.subject | Self-test | pt_BR |
dc.title | Rapid antigen test as a tool for the identification of SARS-CoV-2 infection and its potential as a self-testing device. | pt_BR |
dc.type | Artigo publicado em periodico | pt_BR |
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