DEALI - Departamento de Alimentos

URI permanente desta comunidadehttp://www.hml.repositorio.ufop.br/handle/123456789/540

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2007 - 200912010 - 20112

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Autor: search.filters.author.Vieira, Francilene Gracieli KunradiAssunto: search.filters.subject.Breast cancer

Resultados da Pesquisa

Agora exibindo 1 - 3 de 3
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    Breast cancer in Southern Brazil : association with past dietary intake.
    (2007) Pietro, Patrícia Faria Di; Medeiros, N. I.; Vieira, Francilene Gracieli Kunradi; Fausto, Maria Arlene; Klein, Adriane Belló
    OBJECTIVE: To determine possible associations between the risk of breast cancer in Brazilian women and demographic, social and economical variables, and past dietary intake. METHODS: A case-control study was conducted in Joinville, Santa Catarina, Brazil, between june and november 2003 involving a group of 33 women recently diagnosed with breast cancer and a control group of 33 healthy women volunteers. Personal details, health history and past dietary intake were obtained via questionnaires and interviews. Data between groups were compared using chi2, Fisher, and Student's t test, whilst associations were evaluated using a non-conditional logistic regression method and odds ratio (OR). RESULTS: Statistically significant differences between the two groups were revealed with respect to age distribution (P = 0.007), family income level (P = 0.02), educational level (P < 0.0001) and attainment of menopause (P < 0.0001). After adjustment, with regard to family income level, of the data concerning past dietary intake, the consumption of pig lard (OR = 6.32) and fatty red meat (OR = 3.48) were found to be associated with an increase in the risk of breast cancer. The regular ingestion of apples (OR = 0.30), watermelons (OR = 0.31), tomatoes (OR = 0.16), plain cakes (OR = 0.30) and desserts (OR = 0.20) afforded some degree of protection against the development of the disease. CONCLUSIONS: Age (> 45 years), low family income (< $520/month), poor educational level (primary school level or lower) and past regular consumption of pork fat and fatty meat may be factors associated with an increased risk of breast cancer.
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    Dietary intake and oxidative stress in breast cancer : before and after treatments.
    (2011) Rockenbach, Gabriele; Pietro, Patrícia Faria Di; Ambrosi, Cláudia; Boaventura, Brunna Cristina Bremer; Vieira, Francilene Gracieli Kunradi; Crippa, Carlos Gilberto; Silva, Edson Luiz da; Fausto, Maria Arlene
    Objective: The aim of this study was to investigate changes in dietary intake, anthropometric parameters and markers of oxidative stress in 40 women who underwent surgery, chemotherapy or radiation therapy for breast cancer. Methods: Pretreatment and post-treatment measurements included data collected through a food frequency questionnaire, weight and height to calculate the body mass index (BMI) and oxidative stress markers assessed from blood reduced glutathione (GSH), serum antioxidant capacity (AC), plasma thiobarbituric acid reactive substances (TBARS), serum lipid hydroperoxides (LH) and plasma carbonyls. Differences were compared using paired Student’s t-test or paired Wilcoxon’s test. Results: A significant increase (P < 0.05) in the intake of the food groups: meat and eggs, dairy products, beans, oils and fats, as well as food from the subgroups: red meat, milk and other dairy products rich in fat, fruit rich in vitamin C and vegetable fats was found after treatments. There was a significant increase in body weight (P < 0.05), BMI (P < 0.05), levels of TBARS (P < 0.0001), LH (P < 0.005) and carbonyls (P < 0.0001) and a significant decrease of levels of AC (P < 0.005) and GSH (P < 0.0001). Conclusion: Breast cancer diagnosis and treatments were associated with dietary intake changes and increased body weight, BMI and oxidative stress. These potential changes have important implications for preventive nutrition counseling.
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    Factors associated with oxidative stress in women with breast cancer.
    (2011) Vieira, Francilene Gracieli Kunradi; Pietro, Patrícia Faria Di; Boaventura, Brunna Cristina Bremer; Ambrosi, Cláudia; Rockenbach, Gabriele; Fausto, Maria Arlene; Crippa, Carlos Gilberto; Silva, Edson Luiz da
    Objective: To assess the association between physiological, physical, lifestyle and nutritional variables and oxidative stress biomarkers in women with breast cancer. Methods: This cross-sectional study was conducted on 55 women newly diagnosed with breast cancer. The extent of oxidative stress was analyzed by the measurement of plasma lipid hydroperoxides (LH), thiobarbituric acid reactive substances (TBARS), protein carbonyl, whole blood reduced glutathione (GSH) and serum antioxidant capacity (AC). Diet data were obtained from food frequency questionnaire. Linear regression was used to determine the association between the variables studied and oxidative stress biomarkers. The protein carbonyl data was not included in the linear regression analyses since the data did not show a normal distribution, even after logarithmic and other transformations. Results: After adjusting for energy intake, the intake of chicken and high-fat dairy products was associated with increased levels of LH, while vitamin E intake was associated with decreased LH levels (R2 = 23.8%). Intake of oils was associated with increased levels of TBARS (R2 = 6.82%). Positive axillary lymph node status was associated with decreased levels of GSH (R2 = 9.31%). Increasing age was directly associated with levels of AC, while animal fat, dairy product, and sweet food intakes were associated with low levels of AC (R2 = 41.42%). Conclusion: Intake of chicken, vitamin E, dairy products (particularly high-fat dairy products), oils, animal fat, and sweet foods, along with axillary lymph node status and age, may be important determinants of oxidative stress in women with breast cancer.