Diniz, Mirla FiuzaSiqueira, Sávio LanaBaumfeld, Tiago SoaresPereira, Luis Felipe CintraMoreira, Filipe GarciaRibeiro, Gustavo MeirellesSouza, Iure Kalinine Ferraz de2016-07-292016-07-292015DINIZ, M. F. et al. Analysis of liver fragment subjected to autologous transplant at rat’s retroperitoneum. The Journal of Surgical Research (Print), v. 199, p. 407-411, 2015. Disponível em: <http://www.sciencedirect.com/science/article/pii/S0022480415007106>. Acesso em: 16 jun. 2016.0022-4804http://www.repositorio.ufop.br/handle/123456789/6676Background: To investigate the regeneration process of autologous implants of liver on the retroperitoneum. Methods: Thirty male Fisher rats were used divided in to group 1 (G1): studied 60 d after surgery; group 2 (G2): studied 90 d after surgery; group 3 (G3): studied 180 d after surgery; and group C (GC): animals without surgery. Hepatic fragment was processed for histologic and biochemical analysis. Results: There was inflammatory infiltrate, diffuse hydropic degeneration, necrosis, and moderate fibrosis that reduced in direct relation to the postsurgical time. The concentration of albuminwas differentbetweenGCandG1 and betweenG1 andG3 (P¼0.0007).The Catalase (CAT) was related to the time of surgery with GC being different when compared with G1, G2, and G3 (P < 0.0001). The oxidative stress measured through the thiobarbituric acid reactive substances lipid peroxidation was different between the GC and the G2 groups (P ¼ 0.0381). Conclusions: The analysis made showed hepatic regeneration in the fragment subjected to autologous transplant at the retroperitoneumen-USabertoHepatic regenerationAutotransplantationExperimental surgeryArtigo publicado em periodicoO periódico Journal of Surgical Research concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3894850393265.https://doi.org/10.1016/j.jss.2015.06.029