Lana, Gwenaelle Elza Nathalie PoundRabanel, Jean MichelHildgen, PatriceMosqueira, Vanessa Carla Furtado2017-08-312017-08-312017LANA, G. E. N. P. et al. Functional polylactide via ring-opening copolymerisation with allyl, benzyl and propargyl glycidyl ethers. European Polymer Journal, v. 90, p. 344-353, 2017. Disponível em: <http://www.sciencedirect.com/science/article/pii/S0014305717300447>. Acesso em: 29 ago. 2017.0014-3057http://www.repositorio.ufop.br/handle/123456789/8639A versatile and simple strategy is presented to synthesize reactive polylactide derivatives and their block copolymers with polyethylene glycol. Commercially available glycidyl ethers with an allyl, benzyl or propargyl functional group were copolymerised with D,L-lactide. Tin(II)-2- ethylhexanoate-catalysis produced polymers with up to 4.6, 5.9 and 2.3 allyl, benzyl or propargyl groups per chain, respectively. In contrast, less than one reactive group per chain was obtained with the organocatalyst 1,5,7-triazabicyclo[4.4.0]dec-5-ene. By increasing the polymerisation feed ratio in glycidyl ether polymers with a higher number of reactive groups per chain were obtained, however a decrease in molar mass was observed. An azidocoumarin was conjugated to the propargylated polymers via copper-catalysed azide-alkyne cycloaddition. These dye-labelled polymers produced nanospheres with fluorescent properties and diameters in the 100-nm sizerange, as characterised by asymmetric flow field flow fractionation hyphenated with fluorescence, static and dynamic light scattering detection. The functionalised polymers were obtained at gram-scale in one step from commercially available reagents; therefore providing a robust and easy to implement approach for the production of multifunctional nanomaterials.en-USabertoEpoxidePolymer-conjugateFluorescent probeAzide-alkyne cycloadditionPolymeric nanoparticlesArtigo publicado em periodicoO periódico European Polymer Journal concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 4178720595540.https://doi.org/10.1016/j.eurpolymj.2017.03.028