Lana, Marta deChiari, Cléa de AndradeChiari, EglerMorel, Carlos MedicisGonçalves, Antônio M.Romanha, Alvaro José2017-03-312017-03-311996LANA, M. de et al. Characterization of two isolates of Trypanosoma cruzi obtained from the patient Berenice, the first human case of Chagas disease. Parasitology Research, v. 82, p. 257-260, 1996. Disponível em: <http://link.springer.com/article/10.1007/s004360050106>. Acesso em: 20 jan. 2017.1432-1955http://www.repositorio.ufop.br/handle/123456789/7515Two isolates of Trypanosoma cruzi were obtained from the patient Berenice, the first human case of Chagas’ disease (Chagas 1909), when she was 55 and 71 years old, respectively. The isolates were characterized on the basis of their epimastigote-trypomastigote differentiation in liquid media and of the electrophoretic pattern of EcoR1 digestion products of kinetoplast DNA (k- DNA) minicircles (schizodeme) and isoenzyme patterns (zymodeme). Clear differences were found between the isolates, suggesting the occurrence of a heterogeneous population of T. cruzi in the infection of this patient.en-USrestritoArtigo publicado em periodicohttp://link.springer.com/article/10.1007/s004360050106https://doi.org/10.1007/s004360050106