Paula, Heberth dePedrosa, Maria LúciaRossoni Júnior, Joamyr VictorHaraguchi, Fabiano KenjiSantos, Rinaldo Cardoso dosSilva, Marcelo Eustáquio2015-03-242015-03-242009PAULA, H. de et al. Effect of an aqueous extract of annatto (Bixa orellana) seeds on lipid profile and biochemical markers of renal and hepatic function in hipercholesterolemic rats. Brazilian Archives of Biology and Technology, v. 52, p. 1373-1378, 2009. Disponível em: <http://www.scielo.br/scielo.php?pid=S1516-89132009000600008&script=sci_abstract>. Acesso em: 08 nov. 2014.1516-8913http://www.repositorio.ufop.br/handle/123456789/4735Annatto extract is a natural food color obtained from the outer coatings of the seeds of the Annatto tree (Bixa orellana L.). This is the first report in the literature that shows the relationship between the aqueous annatto extract and its influence on lipid profile in animals. Male Fisher rats were divided into three groups (n=12): C group, fed standard diet and water; H group, fed high-lipid diet and water and; HU group, with high-lipid diet and aqueous annatto extract for 60 days. The treatment with annatto extract in animals fed with the high-lipid diet lowered the LDL- and total cholesterol and raised the HDL-cholesterol, suggesting a hypocholesterolemic effect. Neither highfat diet nor aqueous annatto extract had any significant effect on serum levels of albumin or serum activities of transaminases which suggested that no liver injury was induced.en-USAnnattoBixa orellanaCholesterolAqueous extractLipid profileArtigo publicado em periodicoO periódico Brazilian Archives of Biology and Technology permite que o Repositório Institucional da Universidade Federal de Ouro Preto (UFOP) deposite uma cópia eletrônica dos artigos publicados por esse periódico  em que ao menos um dos autores faça parte da comunidade cientifica da UFOP. Fonte: Licença concedida mediante preenchimento de formulário enviado em 29 jan. 2014.http://dx.doi.org/10.1590/S1516-89132009000600008