Silva, Rosangela Maria Ferreira da Costa eDiniz, Ivana Márcia AlvesGomes, Natália AparecidaSilva, Guilherme Jorge BrigoliniFerreira, José Maria da FonteFreitas Filho, Rubens Lucas deFreitas, Erico Tadeu FragaMartins, Darliane AparecidaDomingues, Rosana ZacariasAndrade, Ângela Leão2023-07-272023-07-272022SILVA, R. M. F. da C. e et al. Equisetum hyemale‑derived unprecedented bioactive composite for hard and soft tissues engineering. Scientific Reports, v. 12, artigo 13425, 2022. Disponível em: <https://www.nature.com/articles/s41598-022-17626-w>. Acesso em: 15 mar. 2023.2045-2322http://www.repositorio.ufop.br/jspui/handle/123456789/17097Although Bioactive Glasses (BGs) have been progressively optimized, their preparation often still involves the use of toxic reagents and high calcination temperatures to remove organic solvents. In the present work, these synthesis related drawbacks were overcome by treating the ashes from the Equisetum hyemale plant in an ethanol/water solution to develop a bioactive composite [glass/ carbon (BG-Carb)]. The BG-Carb was characterized by scanning electron microscopy, and transmission electron microscopy; and its chemical composition was assessed by inductively coupled plasmaoptical emission spectroscopy. Brunauer–Emmett–Teller gas adsorption analysis showed a specifc surface area of 121 m2 ­g−1. The formation of hydroxyapatite (HA) surface layer in vitro was confrmed by Fourier-transform infrared spectroscopy analysis before and after immersion in simulated body fuid (SBF) solution. The Rietveld refnement of the XRD patterns and selected area electron difraction analyses confrmed HA in the sample even before immersing it in SBF solution. However, stronger evidences of the presence of HA were observed after immersion in SBF solution due to the surface mineralization. The BG-Carb samples showed no cytotoxicity on MC3T3-E1 cells and osteodiferentiation capacity similar to the positive control. Altogether, the BG-Carb material data reveals a promising plant waste-based candidate for hard and soft tissue engineering.en-USabertoArtigo publicado em periodicoThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. Te images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. Fonte: PDF do artigo.https://doi.org/10.1038/s41598-022-17626-w