Andrade, Dayse Rodrigues de SousaCamelo, Lidyane do ValleReis, Rodrigo Citton Padilha dosSantos, Itamar de SouzaRibeiro, Antônio Luiz PinhoGonçalves, Luana GiattiBarreto, Sandhi Maria2017-11-082017-11-082016ANDRADE. D. R. S. et al. Life course socioeconomic adversities and 10-year risk of cardiovascular disease: cross-sectional analysis of the Brazilian Longitudinal Study of Adult Health. International Journal of Public Health, v. 62, p. 283-292, 2016. Disponível em: <https://link.springer.com/article/10.1007/s00038-016-0928-3>. Acesso em: 29 ago. 2017.1661-8564http://www.repositorio.ufop.br/handle/123456789/9106Objectives To investigate whether life course exposure to adverse socioeconomic positions (SEP) as well as maintaining a low SEP or decreasing the SEP intra- and intergeneration was associated with an increased 10-year cardiovascular disease (CVD) risk predicted by the Framingham Risk Score. Methods This is a cross-sectional analysis of baseline data (2008–2010) of 13,544 active workers from ELSA-Brasil cohort. Maternal education, leg length, social class of first occupation and education were used to evaluate childhood, youth and adulthood SEP. Results After considering adulthood SEP, exposure to early-life low SEP remained associated with an increased 10-year CVD risk. The 10-year CVD risk also rose as the number of exposures to low SEP throughout life increased. Compared to individuals in high-stable intragenerational trajectory, those in upward, downward, or stable low trajectory presented higher 10-year CVD risk. Increasing individuals’ SEP over generation showed no increased risk of 10-year CVD risk compared to individuals in highstable trajectory. Conclusions Childhood may be a critical period for exposures to social adversities. Life course low SEP may also affect the 10-year CVD risk via accumulation of risk and social mobility.en-USrestritoSocioeconomic positionSocial mobilityFramingham Risk ScoreArtigo publicado em periodicohttps://link.springer.com/article/10.1007/s00038-016-0928-3https://doi.org/10.1007/s00038-016-0928-3