Li, Xiao HongDeMarco, RicardoNeves, Leandro XavierJames, Sally R.Newling, KatherineAshton, Peter D.Cao, Jian PingWilson, R. AlanBorges, William de Castro2018-05-112018-05-112018LI, X. H. et al. Microexon gene transcriptional profiles and evolution provide insights into blood processing by the Schistosoma japonicum esophagus. PLoS Neglected Tropical Diseases, v. 12, p. 1-22, 2018. Disponível em: <http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0006235>. Acesso em: 05 abr. 2018.19352735http://www.repositorio.ufop.br/handle/123456789/9919Adult schistosomes have a well-developed alimentary tract comprising an oral sucker around the mouth, a short esophagus and a blind ending gut. The esophagus is not simply a muscular tube for conducting blood from the mouth to gut but is divided into compartments, surrounded by anterior and posterior glands, where processing of ingested blood is initiated. Self-cure of rhesus macaques from a Schistosoma japonicum infection appears to operate by blocking the secretory functions of these glands so that the worms cease feeding and slowly starve to death. Here we use subtractive RNASeq to characterise the genes encoding the principal secretory products of S. japonicum esophageal glands, preparatory to evaluating their relevance as targets of the self-cure process.en-USabertoArtigo publicado em periodicoThis is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Fonte: Plos One <http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0172103> .Acesso em: 30 jul. 2017.