Artiguenave, FrançoisAquino, André Luiz Lins deMaciel, Wesley DiasCaldeira Júnior, Antônio CelsoCoelho, Carla NacifLinhares, Maria Margarida Ribeiro de SouzaOliveira, Guilherme Corrêa deBarbosa, Luis Humberto RezendeLopes, Júlio César DiasCoelho Júnior, Claudionor José Nunes2012-07-122012-07-122005ARTIGUENAVE, F. The tropical biominer project : mining old sources for new drugs. OMICS: A Journal of Integrative Biology, v. 9, n.2, p.130-138, 2005. Disponível em: <http://online.liebertpub.com/doi/pdf/10.1089/omi.2005.9.130>. Acesso em: 12 jul. 2012.15362310http://www.repositorio.ufop.br/handle/123456789/1102The tropical biominer project: mining old sources for new drugs The Tropical Biominer Project is a recent initiative from the Federal University of Minas Gerais (UFMG) and the Oswaldo Cruz foundation, with the participation of the Biominas Foundation (Belo Horizonte, Minas Gerais, Brazil) and the start-up Homologix. The main objective of the project is to build a new resource for the chemogenomics research, on chem-ical compounds, with a strong emphasis on natural molecules. Adopted technologies include the search of information from structured, semi-structured, and non-structured documents (the last two from the web) and datamining tools in order to gather information from dif-ferent sources. The database is the support for developing applications to find new poten-tial treatments for parasitic infections by using virtual screening tools. We present here the midpoint of the project: the conception and implementation of the Tropical Biominer Data-base. This is a Federated Database designed to store data from different resources. Con-nected to the database, a web crawler is able to gather information from distinct, patented web sites and store them after automatic classification using datamining tools. Finally, we demonstrate the interest of the approach, by formulating new hypotheses on specific targets of a natural compound, violacein, using inferences from a Virtual Screening procedure.en-USArtigo publicado em periodicoO periódico OMICS permite o depósito da versão PDF do editor em Repositório Institucional. Fonte: Sherpa/Romeo <http://www.sherpa.ac.uk/romeo/search.php?issn=1536-2310> Acesso em 15 dez. 2013.