Guarda, Vera Lúcia de MirandaPerrissin, MoniqueThomasson, FrançoisXimenes, Eulália Camelo Pessoa de AzevedoGaldino, Suely LinsPitta, Ivan da RochaLuu-Duc, Cuong2017-04-262017-04-262000GUARDA, V. L. de M. et al. Synthesis and microbiological activity of some 2H-1,4-benzothiazin-3-one derivatives. Heterocyclic Communications, v. 06, n.01, p. 35-40, 2000. Disponível em: <https://www.degruyter.com/view/j/hc.2000.6.1/hc.2000.6.1.49/hc.2000.6.1.49.xml>. Acesso em: 20 jan. 2017.2191-0197http://www.repositorio.ufop.br/handle/123456789/7636The synthesis and physicochemical properties of 4-butyl-2H-benzo[1,4]thiazin-3-one derivatives are described. These new compounds were synthesised by alkylation in 4-N position and acylation and/or alkylation of 6-NH2 by phase transfer catalysis. Acid hydrolysis of 6-alkylacylamino group yielded 6-alkylamino-4-butyl-2H-benzo[1,4]thiazin-3-ones. The antimicrobial in vitro activity was determined on five compounds.en-USrestritoBenzothiazinesAntimicrobial activityArtigo publicado em periodicohttps://www.degruyter.com/view/j/hc.2000.6.1/hc.2000.6.1.49/hc.2000.6.1.49.xmlhttps://doi.org/10.1515/HC.2000.6.1.49