Meléndez Salazar, Gloria Del CarmenSousa, Grasiely Faria deDuarte, Lucienir PainsSilva, Roqueline RodriguesVieira Filho, Sidney AugustoSilva, Grácia Divina de Fátima2022-12-072022-12-072021MELÉNDEZ SALAZAR, G. D. C. et al. Truncatin a: triterpene dimer isolated from Maytenus truncata Reissek (Celastraceae). World Journal of Pharmacy and Pharmaceutical Sciences, v. 10, n. 7, p. 60-71, 2021. Disponível em: <https://www.wjpps.com/Wjpps_controller/abstract_id/14580>. Acesso em: 11 out. 2022.2278 – 4357http://www.repositorio.ufop.br/jspui/handle/123456789/15870Maytenus truncata Ressek is a medicinal plant naturally found in Cerrado biome of Brazil. The tea from its leaves is used to treat gastrointestinal disorders. Such as other species of the Celastraceae family, the aerial parts, and roots of Maytenus truncata are rich in pentacyclic triterpenes. Roots of M. truncata were subjected to chromatographic methods that culminated in the isolation of a dimer pentacyclic triterpene termed truncatin. The structure of truncatin was established based on FT-IR, 1D/2D NMR, including DEPT-135, HSQC, HMBC and COSY spectra, and mass spectrometry. The compound was characterized as containing a quinone methide friedelane-type unit linked to another unit constituted by a skeleton similar to those of lupane series. These two units are linked together through the respective ring A, by two ether linkages. This work presents for the first time, the skeleton lupane as a unit of a dimer of pentacyclic triterpenes.en-USrestritoPentacyclic triterpene dimerHetero Diels - Alder reactionArtigo publicado em periodicohttps://www.wjpps.com/Wjpps_controller/abstract_id/1458