Santos, Kelly Fabiane RicardoOliveira, Tânia Toledo deNagem, Tanus JorgePinto, Aloísio da SilvaOliveira, Maria Goreti de Almeida2012-05-292012-05-291999SANTOS, K. F. R. et al. Hypolipidaemic effects of naringenin, rutin, nicotinic acid and their associations. Pharmacological Research, v. 40, n.6, p.493-496, 1999. Disponivel em: <https://www.sciencedirect.com/science/article/pii/S104366189990556X>. Acesso em: 29 maio 2012.10436618http://www.repositorio.ufop.br/handle/123456789/800Atherosclerosis can be defined as being a disease of coronary circulation. The present workevaluates the action of the naringenin, rutin, nicotinic acid, isolated and in association, on the metabolism of lipids. Cholesterol, cholesterol HDL, and triacylglycerols have been dosed after retreat of blood, following the administration of the compounds dissolved in propylene glycol by intraperitoneal route in doses of 5 mg kgy1 body wt. Results evidence that naringenin and nicotinic acid, isolated as well as their association with naringenin and nicotinic acid ] rutin, present the largest percentual reduction of cholesterol. On the other hand, the best results for cholesterol-HDL have been obtained with naringenin, while rutin has shown the best triacylglycerols levels.pt-BRNaringeninRutinNicotinic acidHipolipidemic actionRatsArtigo publicado em periodicoO periódico Pharmacological Research concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3582471027485.