Differential expression of cocaine- and amphetamine-regulated transcript-immunoreactivity in the rat spinal preganglionic nuclei.
dc.contributor.author | Dun, S. L. | |
dc.contributor.author | Chianca Júnior, Deoclécio Alves | |
dc.contributor.author | Dun, Nae J. | |
dc.contributor.author | Yang, J. | |
dc.contributor.author | Chang, Jaw-Kang | |
dc.date.accessioned | 2015-01-20T15:38:28Z | |
dc.date.available | 2015-01-20T15:38:28Z | |
dc.date.issued | 2000 | |
dc.description.abstract | The distribution of cocaine- and amphetamine-regulated transcript-like immunoreactivity (CART-LI) was investigated in the rat spinal cords with the use of an antiserum against the CART peptide fragment 55±102. CART-LI ®bers were concentrated in the super®cial layers of the dorsal horn of all segments. In addition to CART-LI ®bers, intensely labeled somata were detected in the intermediolateral cell column (IML) and other sympathetic preganglionic nuclei of the thoracolumbar segments. In the lumbosacral segments, CART-LI ®bers but not somata were seen in the sacral parasympathetic nucleus. Double-labeling the spinal sections with choline acetyltransferase (ChAT)-antisera and CARTantisera revealed that the large majority of ChAT-positive somata in the sympathetic preganglionic nuclei were CARTpositive, whereas ChAT-positive somata in the parasympathetic preganglionic nuclei were CART-negative. Our results show that CART-LI is selectively expressed in a population of sympathetic preganglionic neurons (SPNs), but not in parasympathetic preganglionic neurons (PPNs) of the rat. | pt_BR |
dc.identifier.citation | DUN, S. L. et al. Differential expression of cocaine- and amphetamine-regulated transcript-immunoreactivity in the rat spinal preganglionic nuclei. Neuroscience Letters. Supplement, USA, v. 294, n.3, p. 143-146, 2000. Disponível em: <http://www.sciencedirect.com/science/article/pii/S0304394000015755>. Acesso em: 08 nov. 2014. | pt_BR |
dc.identifier.doi | https://doi.org/10.1016/S0304-3940(00)01575-5 | |
dc.identifier.issn | 0304-3940 | |
dc.identifier.uri | http://www.repositorio.ufop.br/handle/123456789/4283 | |
dc.language.iso | en_US | pt_BR |
dc.rights.license | O periódico Neuroscience Letters concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3521411315026. | pt_BR |
dc.subject | Neurons | pt_BR |
dc.subject | Spinal cord | pt_BR |
dc.subject | Cell column | pt_BR |
dc.title | Differential expression of cocaine- and amphetamine-regulated transcript-immunoreactivity in the rat spinal preganglionic nuclei. | pt_BR |
dc.type | Artigo publicado em periodico | pt_BR |
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