The impact of the stratification by degree of clinical severity and abandonment risk of tuberculosis treatment.
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2021
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Objective: Evaluate the impact of the instrument of the “Stratification by Degree of
Clinical Severity and Abandonment Risk of Tuberculosis Treatment” (SRTB) on the
tuberculosis outcome. Methods: This study was a pragmatic clinical trial involving
patients with a confirmed diagnosis of tuberculosis treated at one of the 152 primary
health care units in the city of Belo Horizonte, Brazil, between May of 2016 and
April of 2017. Cluster areas for tuberculosis were identified, and the units and their
respective patients were divided into intervention (use of SRTB) and nonintervention
groups. Results: The total sample comprised 432 participants, 223 and 209 of whom
being allocated to the nonintervention and intervention groups, respectively. The risk
of treatment abandonment in the nonintervention group was significantly higher than
was that in the intervention group (OR = 15.010; p < 0.001), regardless of the number
of risk factors identified. Kaplan-Meier curves showed a hazard ratio of 0.0753 (p <
0.001). Conclusions: The SRTB instrument was effective in reducing abandonment of
tuberculosis treatment, regardless of the number of risk factors for that. This instrument
is rapid and easy to use, and can be adapted to different realities. Its application showed
characteristics predisposing to a non-adherence to the treatment and established bases
to mitigate its impact.
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Patient compliance, Risk factors, Treatment adherence, Cooperação do paciente, Fatores de risco
Citação
NAVARRO, P. D. de et al. The impact of the stratification by degree of clinical severity and abandonment risk of tuberculosis treatment. Jornal Brasileiro de Pneumologia, v. 47, artigo e20210018-21, 2021. Disponível em: <https://www.scielo.br/j/jbpneu/a/CPN8Z3BP3mY6ZzCLmZxTxDz/?lang=en>. Acesso em: 11 out. 2022.