Xanthones and Phenylcoumarins from Kielmeyera pumila.

Abstract

In continuation of our studies on extracts of the Guttiferae family we have examined the stems and fruit of Kielmeyera pumila Pohl, collected in the region of Ouro Preto, State of Minas Gerais, from a specimen identified by the botanist Jo& Badini (Herb. Prof. JosC Badini, Universidade Federal de Ouro Preto, Minas Gerais, Brazil). Several species of this genus has been shown to contain xanthones [l]. Investigation of the stems of the K. pumih has yielded, besides sitosterol, two previously known xanthones (osajaxanthone [Z] and 6-deoxyjacareubin [3]) and two known phenylcoumarins, the 1,2-dihydro-5- hydroxy-2-(l-hydroxy-l-methylethyl)-4-(3-methylbutyryl)- 6-phenyl-furo [2,3-h] [l] benzopyran-8-one [4] and mammeigin (1) [S]. The fruit of the same plant yielded friedelin, a-amyrin, shikimic acid, mammeigin and an isomer of mammeigin to which we have given the trivial name isomammeigin (2).