Comprehensive untargeted metabolomics of Lychnnophorinae subtribe (Asteraceae: Vernonieae) in a phylogenetic context.

dc.contributor.authorMartucci, Maria Elvira Poleti
dc.contributor.authorLoeuille, Benoît Francis Patrice
dc.contributor.authorPirani, Jose Rubens
dc.contributor.authorGobbo Neto, Leonardo
dc.date.accessioned2019-04-17T15:53:10Z
dc.date.available2019-04-17T15:53:10Z
dc.date.issued2018
dc.description.abstractMembers of the subtribe Lychnophorinae occur mostly within the Cerrado domain of the Brazilian Central Plateau. The relationships between its 11 genera, as well as between Lychnophorinae and other subtribes belonging to the tribe Vernonieae, have recently been investigated upon a phylogeny based on molecular and morphological data. We report the use of a comprehensive untargeted metabolomics approach, combining HPLC-MS and GC-MS data, followed by multivariate analyses aiming to assess the congruence between metabolomics data and the phylogenetic hypothesis, as well as its potential as a chemotaxonomic tool. We analyzed 78 species by UHPLC-MS and GC-MS in both positive and negative ionization modes. The metabolic profiles obtained for these species were treated in MetAlign and in MSClust and the matrices generated were used in SIMCA for hierarchical cluster analyses, principal component analyses and orthogonal partial least square discriminant analysis. The results showed that metabolomic analyses are mostly congruent with the phylogenetic hypothesis especially at lower taxonomic levels (Lychnophora or Eremanthus). Our results confirm that data generated using metabolomics provide evidence for chemotaxonomical studies, especially for phylogenetic inference of the Lychnophorinae subtribe and insight into the evolution of the secondary metabolites of this group.pt_BR
dc.identifier.citationMARTUCCI, M. E. P. et al. Comprehensive untargeted metabolomics of Lychnnophorinae subtribe (Asteraceae: Vernonieae) in a phylogenetic context. PLos One , v. 13, n. 1, p. 1-13, jan. 2018. Disponível em: <https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0190104>. Acesso em: 25 fev. 2019.pt_BR
dc.identifier.issn1935-2735
dc.identifier.urihttp://www.repositorio.ufop.br/handle/123456789/11069
dc.language.isoen_USpt_BR
dc.rightsabertopt_BR
dc.rights.licenseThis is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Fonte: o próprio artigo.pt_BR
dc.titleComprehensive untargeted metabolomics of Lychnnophorinae subtribe (Asteraceae: Vernonieae) in a phylogenetic context.pt_BR
dc.typeArtigo publicado em periodicopt_BR

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