Photodegradable MEH-PPV in a natural rubber matrix : toward a biocompatible colorimetric film for real-time light dosimetry.
Data
2019
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Resumo
This paper reports an interesting strategy of incorporating a photodegradable polymeric luminophore, the poly
[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] - OC10C6-PPV (MEH-PPV), in an inert natural rubber
(Hevea brasiliensisis) - C5H8 (NR) matrix for monitoring and recording the radiation dose administered to patients
under phototherapy, particularly in the treatment for jaundice newborns. A time-trend spectrofluorimetric
study has been carried out to characterize the luminescent changes of the MEH-PPV/NR luminophore system
upon photodegradation by realistic conditions of phototherapy treatment, and the dependence between color
and dose was used to determine the dose-response relationships of this color film dosimeter. Cytotoxicity tests
(CHO-K1 cell line) have also been conducted on extracts of the OC10C6-PPV/C5H8 before and after photolysis.
The experimental results reported here highlight the potential application of photodegradable polymer/natural
rubber as a biocompatible skin-mountable patch to monitor light exposure to improve patient care in phototherapy,
photodynamic, lasers and radiation therapies.
Descrição
Palavras-chave
Semiconducting polymer, Organic device, Printable device, Photooxidation, Dosimeter
Citação
BRAGA, N. O. et al. Photodegradable MEH-PPV in a natural rubber matrix : toward a biocompatible colorimetric film for real-time light dosimetry. Journal of Luminescence, v. 210, p. 501–507, jun. 2019. Disponível em: <https://www.sciencedirect.com/science/article/pii/S0022231318315813>. Acesso em: 19 mar. 2019.