Polymorphisms in genes coding milk proteins and protein hormones involved in milk production traits in Brazilian Guzerá cattle.
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2022
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Resumo
Research on genes affecting phenotypic variation in
milk production and composition from indicine (Bos indicus) cattle is
imperative, since these breeds are important tropical genetic
resources, and there have been few studies investigating the genetic
basis of these traits. We identified polymorphisms in -casein
(CSN3), -lactoglobulin (LGB), thyroglobulin (TG) and prolactin
(PRL) and examined their effect on milk and composition traits in the
Guzerá breed. DNA samples of 260 Guzerá cattle selected for dual
purpose use were genotyped. Allele frequencies observed for the A
allele were 0.83, 0.18 and 0.25 respectively for CSN3, LGB and PRL
genes, while for the TG gene T allele had an allele frequency of 0.09.
For all polymorphisms evaluated, observed genotypic frequencies
were in agreement with those expected according to the Hardy-
Weinberg Equilibrium hypothesis. A polymorphism association study
evaluated breeding values (BV) for 305-day milk (BV-M), fat (BV-
F), and protein (BV-P) production, employing the allele substitution
model using a sample of 139 cows belonged to 27 full and half-sib families of a MOET (multiple ovulation and embryo transfer)
selection nucleus. Association was found between the LGB
polymorphism and BV-M, BV-F and BV-P. Animals with LGB AA
genotype have, on average, higher BV when compared to animals
with LGB AB and BB genotypes (277.85 kg for BV-M, 12.09 kg for
BV-F and 9.33 kg for BV-P). These findings contribute to a better
understanding on the influence of these polymorphisms on milk
production traits in Guzerá cattle.
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Molecular markers, Dairy cattle, Bos indicus
Citação
SILVA, R. S. da et al. Polymorphisms in genes coding milk proteins and protein hormones involved in milk production traits in Brazilian Guzerá cattle. Genetics and Molecular Research, v. 21, n. 3, 2022. Disponível em: <https://www.geneticsmr.com/articles/polymorphisms-genes-coding-milk-proteins-and-protein-hormones-involved-milk-production>. Acesso em: 01 ago. 2023.