EFAR - Escola de Farmácia
URI permanente desta comunidadehttp://www.hml.repositorio.ufop.br/handle/123456789/451
Notícias
O curso de Farmácia em Ouro Preto foi criado em 1839, sendo a mais antiga Escola de Farmácia da América Latina.
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5 resultados
Resultados da Pesquisa
Item Examining the mental health of the academic community at an institution for higher education during the COVID-19 pandemic.(2022) Paula, Waléria de; Khouri, Isadora Dantas Sakr; Machado, Elaine Leandro; Silva, Glenda Nicioli da; Roever, Leonardo; Meireles, Adriana LúciaDue to the COVID-19 pandemic, the Higher Education Institutions had to suspend their on-site activities and adapt to the new scenario. Therefore, the objective of the research was to investigate the effects of the COVID-19 pandemic on the mental health of the academic community of a Brazilian public university. This is a crosssectional study, at a Brazilian public university, that used the baseline data from a longitudinal study carried out with employees and students. Participants answered a self-administered and confidential questionnaire in online platform, composed of sociodemographic, economic, lifestyles and mental health issues. 1,353 students and 372 employees participated. The prevalence of anxiety disorder symptoms among students and employees was 46.12% and 17.47%, depression 54.62% and 22.85% and stress 47.45% and 22.58%, respectively. The co-occurrence of symptoms was 33.56% among university students and 10.75% among employees. Falling family income, having stopped smoking and negative self-rated health, during the COVID-19 pandemic, may be the reasons for the high prevalence of co-occurrence of anxiety, depression and stress disorders among the academic community.Item Performance of the Wondfo 2019-nCoV antigen test using self-collected nasal versus professional-collected nasopharyngeal swabs in symptomatic SARS-CoV-2 infection.(2022) Cardoso, Jamille Mirelle de Oliveira; Roatt, Bruno Mendes; Vieira, Paula Melo de Abreu; Paiva, Nívia Carolina Nogueira de; Souza, Breno Bernardes; Lisboa, Oscar Campos; Soares, Rodrigo Dian de Oliveira Aguiar; Reis, Alexandre Barbosa; Vital, Wendel Coura; Carneiro, Cláudia MartinsItem Successive pandemic waves with different virulent strains and the effects of vaccination for SARS-CoV-2.(2022) Silva, Alcides Castro e; Bernardes, Américo Tristão; Barbosa, Eduardo Augusto Gonçalves; Chagas, Igor Aparecido Santana das; Dáttilo, Wesley; Reis, Alexandre Barbosa; Ribeiro, Sérvio PontesOne hundred years after the flu pandemic of 1918, the world faces an outbreak of a new severe acute respiratory syndrome, caused by a novel coronavirus. With a high transmissibility, the pandemic has spread worldwide, creating a scenario of devastation in many countries. By the middle of 2021, about 3% of the world population had been infected and more than 4 million people had died. Different from the H1N1 pandemic, which had a deadly wave and ceased, the new disease is maintained by successive waves, mainly produced by new virus variants and the small number of vaccinated people. In the present work, we create a version of the SIR model using the spatial localization of persons, their movements, and considering social isolation probabilities. We discuss the effects of virus variants, and the role of vaccination rate in the pandemic dynamics. We show that, unless a global vaccination is implemented, we will have continuous waves of infections.Item Strategies to improve antimicrobial utilization with a special focus on developing countries.(2021) Godman, Brian; Nascimento, Renata Cristina Rezende Macedo do; Seaton, Ronald AndrewAntimicrobial resistance (AMR) is a high priority across countries as it increases morbidity, mortality and costs. Concerns with AMR have resulted in multiple initiatives internationally, na- tionally and regionally to enhance appropriate antibiotic utilization across sectors to reduce AMR, with the overuse of antibiotics exacerbated by the COVID-19 pandemic. Effectively tackling AMR is crucial for all countries. Principally a narrative review of ongoing activities across sectors was undertaken to improve antimicrobial use and address issues with vaccines including COVID-19. Point prevalence surveys have been successful in hospitals to identify areas for quality improvement programs, principally centering on antimicrobial stewardship programs. These include reducing prolonged antibiotic use to prevent surgical site infections. Multiple activities centering on education have been successful in reducing inappropriate prescribing and dispensing of antimicrobials in ambulatory care for essentially viral infections such as acute respiratory infections. It is imperative to develop new quality indicators for ambulatory care given current concerns, and instigate programs with clear public health messaging to reduce misinformation, essential for pandemics. Regular access to effective treatments is needed to reduce resistance to treatments for HIV, malaria and tuberculosis. Key stakeholder groups can instigate multiple initiatives to reduce AMR. These need to be followed up.Item In silico approach of secondary metabolites from Brazilian herbal medicines to search for potential drugs against SARS-CoV-2.(2021) Amparo, Tatiane Roquete; Seibert, Janaína Brandão; Almeida, Tamires Cunha; Costa, Fernanda Senna Ferreira; Silveira, Benila Maria; Silva, Glenda Nicioli da; Santos, Orlando David Henrique dos; Souza, Gustavo Henrique Bianco deThe new severe acute respiratory syndrome coronavirus (SARS-CoV-2) recently emerged as a worrying pandemic, with many confirmed cases and deaths globally. Therefore, there is a clear need for identifying effective therapeutic options and a review of secondary metabolites related to Brazilian herbal medicines was performed as a strategy for the discovery of new antiviral agents. To confirm this potential, an in silico screening of the identified compounds identified was also evaluated. The review was performed by the PubMed database and the selected natural compounds were subjected to in silico analysis such as QSAR, molecular docking and ADMET. 497 secondary metabolites were identified from 23 species. The in silico assays indicated 19 potential anti-SARS-CoV-2 compounds, being triterpenes and phenolic compounds. The indicated compounds showed a high affinity with proteins considered as the main molecular targets against SARS-CoV-2 and parameters indicated low toxicity. In addition to Brazilian medicinal plants, these compounds can be found in other species and they can be a base for the synthesis of other anti-COVID-19 drugs. Therefore, this review is important to conduct researches that address the emerging need for drugs in COVID-19 treatment.