Navegando por Autor "Souza, Ana Maria Alves de"
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Item On the application of knoevenagel condensation for the synthesis of benzylidene benzothiazine compounds and structural study.(2006) Souza, Ana Maria Alves de; Guarda, Vera Lúcia de Miranda; Leite, Lucia Fernanda Cavalcanti da Costa; Barbosa Filho, José Maria; Lima, Maria do Carmo Alves de; Galdino, Suely Lins; Pitta, Ivan da RochaThe synthesis and physico-chemical properties of new 6-acetylamino or 6-benzoyl-amino 2-benzylidene-4-methyl-4Hbenzo[1,4]thiazin-3-ones and 6-benzoylamino or 6-nitro 2-benzylidene-4H-benzo[1,4]thiazin-3-ones are described. These benzylidene benzothiazine compounds were prepared by the Knoevenagel condensation with benzaldehydes. The configurations and conformations of benzylidene benzothiazine derivatives were optimised using the semi-empirical method AM1.