Navegando por Autor "Greco, Dirceu Bartolomeu"
Agora exibindo 1 - 3 de 3
Resultados por página
Opções de Ordenação
Item Effects of dietary intervention on lipids profile of HIV infected patients on antiretroviral treatment (ART).(2013) Figueiredo, Sônia Maria de; Penido, Maria Goretti Moreira Guimarães; Guimarães, Milena Maria Moreira; Machado, Lucas José de Campos; Vieira Filho, Sidney Augusto; Fausto, Maria Arlene; Antunes, Carlos Mauricio de Figueiredo; Greco, Dirceu BartolomeuThe aim of this study was to evaluate the effects of dietary intervention on serum lipids, saturated fatty acids and trans-fatty acids in HIV-infected individuals on ART. This design was a non-randomized, non-controlled nutrition intervention study. The setting was in Referral Center in Infectious and Parasitic Diseases. Subjects: 57 HIV-infected patients, aged 28.4–68.4 years, were recruited from the outpatient clinic of a reference center. Clinical and biochemical data were collected from all before and after nutritional counseling. The majority of patients were male, with at least 8 years of schooling and 38.5% had BMI ≥ 25 kg/m2. Forty-eight (84%) patients had a family history of chronic diseases and the most common were coronary events (50%). All patients were exposed to antiretroviral therapy and 51% were using Protease Inhibitor. Twelve patients (21%) had a very low HDL-cholesterol and 26 patients (45.5%) had hypertriglyceridemia. There were a significant increase in carbohydrate (p=0.02), protein (p=0.04), selenium (p<0.00005), and calcium (P=0.0007) intake and a significant decreased in total lipid (p=0.002), saturated fatty acids (p=0.0004), trans fatty acids (p=0.0005), and cholesterol total (p=0.0004) after dietary intervention. No significant difference was observed in energy, total fiber, polyunsaturated fatty acids and monounsaturated fatty acids after dietary intervention. This study suggested an efficacy of nutritional intervention in the prevention of changes in lipid profile of HIV-positive individuals on ART. These findings also suggest that nutritional intervention should be considered for all patients on ART.Item Prevalence and reasons for refusal to participate in clinical research.(2016) Guimarães, Nathalia Sernizon; Greco, Dirceu Bartolomeu; Fausto, Maria Arlene; Kakehasi, Adriana Maria; Guimarães, Milena Maria Moreira; Tupinambás, UnaíAs informações fornecidas sobre prevalência e os motivos da recusa de voluntários a participar em pesquisa científica são escassas. Este artigo objetiva descrever esses dados em coorte voltada a avaliar morbimortalidade de pessoas vivendo com HIV/AIDS (PVHA), a partir de estudo transversal realizado no Centro de Treinamento e Referência em Doenças Infecciosas e Parasitárias. Foram obtidas as informações: origem, data de nascimento, idade, sexo e motivo do não consentimento, quando aplicável. Falta de tempo para se dedicar a pesquisa foi o principal motivo alegado para o não consentimento (63%), seguido por medo de falta de sigilo (17%). Não houve diferença estatística entre os que aceitaram ou não participar por sexo, idade ou origem do serviço. Consideraram-se elevados os percentuais de recusa de PVHA (40,7%), bem como de falta de tempo disponível para participação (63%).Item Risk factors associated with HIV infection among male homosexuals and bisexuals followed in an open cohort study : Project Horizonte, Brazil (1994-2010).(2014) Silva, Ana Paula; Greco, Marília; Fausto, Maria Arlene; Greco, Dirceu Bartolomeu; Carneiro, MariângelaBackground: There has recently been an increase in HIV infection rates among men who have sex with men (MSM). This study aimed at investigating risk factors associated with incident HIV infection in a MSM cohort–Project Horizonte, Belo Horizonte, Minas Gerais, Brazil. Methodology: This is a nested case-control study in an ongoing open cohort of homosexual and bisexual men, carried out in 1994–2010, during which 1,085 volunteers were enrolled. Each HIV seroconverted volunteer (case) was compared with three randomly selected HIV negative controls, matched by admission date and age (63 years). During follow-up, 93 volunteers seroconverted and were compared with 279 controls. Principal Findings: The risk factors associated with HIV seroconversion were: contact with partner’s blood during sexual relations (OR 3.7; 95% CI 1.2–11.6), attendance at gay saunas in search for sexual partners (OR 2.6; 95% CI 1.3–5.4), occasional intake of alcohol when flirting and engaging in sexual activity (OR 2.5; 95% CI 1.3–5.1), inconsistent use of condoms in receptive anal sex (OR 2.4; 95% CI 1.1–5.4), little interest to look up information about AIDS (OR 2.6; 95% CI 1.0– 6.7) particularly in newspapers (OR 3.4; 95% CI 1.4–8.1). Conclusions: This study shows that MSM are still engaging in risk behavior, such as unprotected anal intercourse, despite taking part in a cohort study on various preventive measures. New preventive strategies in touch with the epidemic’s development and the specificities of this particular population are needed.