Navegando por Autor "Ferraz, Vany Perpetua"
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Item ACE inhibition by astilbin isolated from Erythroxylum gonocladum (Mart.) O.E. Schulz.(2010) Lucas Filho, Milton Dayrell; Silva, Grazielle Caroline da; Côrtes, Steyner de França; Guia, Thiago Rennó dos Mares; Ferraz, Vany Perpetua; Serra, Carla Penido; Braga, Fernão CastroErythroxylum species have several traditional uses in different countries, including the treatment of hypertension. The ethanol extract from E. gonocladum aerial parts, a species endemic to the Brazilian cerrado, elicited a concentration-dependent inhibition of angiotensin converting enzyme (ACE) (pIC50=4.53±0.05). Extract fractionation led to the isolation of two compounds, whose structures were assigned by spectrometric data as astilbin and β-sitosterol, along with a mixture of palmitic, stearic and linolenic acids. This is the first report on the occurrence of these compounds on E. gonocladum. Astilbin promoted significant ACE inhibition in vitro (pIC50=5.86±0.33) and its activity did not differ from captopril, when both compounds were assayed at 10 μM concentration.Item Nutritional composition of insects Gryllus assimilis and Zophobas morio : potential foods harvested in Brazil.(2019) Araújo, Rafael Ribeiro Soares; Benfica, Tatiana Aparecida Ribeiro dos Santos; Ferraz, Vany Perpetua; Santos, Eleonice MoreiraThe use of insects as food represents a more sustainable and adequate production system to meet the growing demand for food. In Brazil, the main insects bred in captivity are intended only for animal feed. This work evaluated the nutritional profile of two insect species - Gryllus assimilis (GA) and Zophobas morio (ZM), grown in Brazil. The results showed that the species GA presented 65.52% of proteins, 21.80% lipids, 8,6% carbohydrates and 408% ashes, and the ZM species 46.80% proteins, 43.64% lipids, 8.17% ashes and 1.39% carbohydrates. The content of palmitic, oleic and linoleic acid was the most expressive in the insects. In relation to the mineral containing calcium, magnesium, iron, and zinc were the minerals with the most expressive concentrations. When compared to other commonly used food sources edible insects can supply significant amounts of proteins, lipids, and minerals a nutritional supply suited to biological needs.