Navegando por Autor "Corrêa, Paulo César Rodrigues Pinto"
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Item An old risk factor for COPD : rest in peace, 15%.(2016) Corrêa, Paulo César Rodrigues PintoItem Could APO-varenicline and cytisine be solutions for the shortage of varenicline in Brazil?(2023) Corrêa, Paulo César Rodrigues Pinto; Chatkin, José MiguelItem Dor irruptiva oncológica : revisão da literatura e análise crítica do seu tratamento.(2015) Lage, Giulia Campos; Cirilio, Priscilla Benfica; Corrêa, Paulo César Rodrigues PintoBreakthrough pain ou dor irruptiva oncológica (DIO) e uma exacerbação da dor em pacientes com dor basal oncológica estabilizada e que já recebem terapia com opioides. O objetivo do estudo foi identificar as melhores terapias farmacológicas para o correto tratamento da condição. Realizou-se pesquisa nas bases de dados MEDLINE e LILACS e foram selecionados artigos que abordavam o tratamento da dor e que comparavam os resultados de diferentes medicações. Dos 38 artigos identificados na busca, os 22 disponíveis (pelo portal Capes ou livremente na internet) foram usados. Trabalhos e pesquisas brasileiros e escritos em português sobre a DIO são escassos, o que pode constituir um empecilho para se instituir o tratamento eficaz da condição em nosso pais. O tratamento convencional com morfina, que ainda e utilizado no Brasil, mostrou-se ineficaz pelo longo tempo de inicio de ação. A partir de evidencias atuais, o CF spray nasal alcançou alto nível de alivio da dor em um tempo mais curto. Esses resultados precisam ser amplamente divulgados em nosso país, uma vez que o tratamento no Brasil e geralmente realizado com morfina.Item EAT-Brazil award for tobacco control : a brief description of its first edition.(2019) Corrêa, Paulo César Rodrigues Pinto; Pereira, Rayanna Mara de Oliveira Santos; Temporão, José Gomes; Cavalcante, Tânia Maria; Lisboa, Oscar Campos; Azevedo, Lucas Guimarães de; Brinker, Titus Josef; Souza, Breno BernardesSmoking is a major global risk factor for preventable death and disability. EAT is an acronym for Education Against Tobacco, a multinational network of physicians and medical students that aims to improve tobacco control by means of school-based prevention targeted at adolescents through counseling, use of software and support materials. The first EAT-Brazil Award, launched in March 2018, was a competition designed to encourage the proposal of objective solutions for tobacco control in Brasil, and identify new talents in the area. Brazilian undergraduate students from any field of study could submit a one-page essay on the subject, competing for the amount of R$ 1000.00 (one thousand reais). There were a total of 39 applicants (20 women and 19 men) from 9 Brazilian states and 18 undergraduate programs, with a mean age of 22.5 years (SD = 3.7). Data from an online anonymous questionnaire answered after the submission of their essays revealed that most applicants were students of institutions from in the state of Minas Gerais (n = 26/39; 66.6%), studied medicine (n = 20/39, 51.3%), and had no prior knowledge of the EAT-Brazil Network (n = 27/39, 69.2%). The winner of the award was Lucas Guimarães de Azevedo, a fourth-year medical student at Federal University of Western Bahia. The next editions of the award should focus on increasing the number of applicants and diversifying their geographical distribution.Item Facial-aging mobile apps for smoking prevention in secondary schools in Brazil : appearance-focused interventional study.(2018) Souza, Breno Bernardes; Pires, Francisco Patruz Ananias de Assis; Madeira, Gustavo Moreira; Rodrigues, Túlio Felício da Cunha; Gatzka, Martina; Heppt, Markus V.; Omlor, Albert J.; Enk, Alexander H.; Groneberg, David A.; Seeger, Werner; Kalle, Christof von; Berking, Carola; Corrêa, Paulo César Rodrigues Pinto; Suhre, Janina Leonie; Alfitian, Jonas; Assis, Aisllan Diego de; Brinker, Titus JosefBackground: Most smokers start smoking during their early adolescence, often with the idea that smoking is glamorous. Interventions that harness the broad availability of mobile phones as well as adolescents' interest in their appearance may be a novel way to improve school-based prevention. A recent study conducted in Germany showed promising results. However, the transfer to other cultural contexts, effects on different genders, and implementability remains unknown. Objective: In this observational study, we aimed to test the perception and implementability of facial-aging apps to prevent smoking in secondary schools in Brazil in accordance with the theory of planned behavior and with respect to different genders. Methods: We used a free facial-aging mobile phone app (“Smokerface”) in three Brazilian secondary schools via a novel method called mirroring. The students’ altered three-dimensional selfies on mobile phones or tablets and images were “mirrored” via a projector in front of their whole grade. Using an anonymous questionnaire, we then measured on a 5-point Likert scale the perceptions of the intervention among 306 Brazilian secondary school students of both genders in the seventh grade (average age 12.97 years). A second questionnaire captured perceptions of medical students who conducted the intervention and its conduction per protocol. Results: The majority of students perceived the intervention as fun (304/306, 99.3%), claimed the intervention motivated them not to smoke (289/306, 94.4%), and stated that they learned new benefits of not smoking (300/306, 98.0%). Only a minority of students disagreed or fully disagreed that they learned new benefits of nonsmoking (4/306, 1.3%) or that they themselves were motivated not to smoke (5/306, 1.6%). All of the protocol was delivered by volunteer medical students. Conclusions: Our data indicate the potential for facial-aging interventions to reduce smoking prevalence in Brazilian secondary schools in accordance with the theory of planned behavior. Volunteer medical students enjoyed the intervention and are capable of complete implementation per protocol.Item Farewell, dear colleague and friend Alberto José de Araújo (August 28, 1954 - September 7, 2021).(2021) Corrêa, Paulo César Rodrigues Pinto; Chatkin, José MiguelItem Five-year review of an international clinical research - training program.(2015) Suemoto, Claudia Kimie; Ismail, Sherine; Corrêa, Paulo César Rodrigues Pinto; Khawaja, Faiza; Jerves, Teodoro; Pesantez, Laura; Germani, Ana Claudia Camargo Gonçalves; Zaina, Fabio; Santos Junior, Augusto Cesar Soares dos; Ferreira, Ricardo Jorge de Oliveira; Singh, Priyamvada; Paulo, Judy Vicente; Matsubayashi, Suely Reiko; Vidor, Liliane Pinto; Andretta, Guilherme; Tomás, Rita; Illigens, Ben M. W.; Fregni, FelipeThe exponential increase in clinical research has profoundly changed medical sciences. Evidence that has accumulated in the past three decades from clinical trials has led to the proposal that clinical care should not be based solely on clinical expertise and patient values, and should integrate robust data from systematic research. As a consequence, clinical research has become more complex and methods have become more rigorous, and evidence is usually not easily translated into clinical practice. Therefore, the instruction of clinical research methods for scientists and clinicians must adapt to this new reality. To address this challenge, a global distance-learning clinical research-training program was developed, based on col¬laborative learning, the pedagogical goal of which was to develop critical thinking skills in clinical research. We describe and analyze the challenges and possible solutions of this course after 5 years of experience (2008–2012) with this program. Through evaluation by students and faculty, we identified and reviewed the following challenges of our program: 1) student engagement and motivation, 2) impact of heterogeneous audience on learning, 3) learning in large groups, 4) enhancing group learning, 5) enhancing social presence, 6) dropouts, 7) quality control, and 8) course management. We discuss these issues and potential alternatives with regard to our research and background.Item Five-year review of an international clinical research-training program.(2015) Suemoto, Claudia Kimie; Ismail, Sherine; Corrêa, Paulo César Rodrigues Pinto; Khawaja, Faiza; Jerves, Teodoro; Pesantez, Laura; Germani, Ana Claudia Camargo Gonçalves; Zaina, Fabio; Santos Junior, Augusto Cesar Soares dos; Ferreira, Ricardo Jorge de Oliveira; Singh, Priyamvada; Paulo, Judy Vicente; Matsubayashi, Suely Reiko; Vidor, Liliane Pinto; Andretta, Guilherme; Tomás, Rita; Illigens, Ben M. W.; Fregni, FelipeThe exponential increase in clinical research has profoundly changed medical sciences. Evidence that has accumulated in the past three decades from clinical trials has led to the proposal that clinical care should not be based solely on clinical expertise and patient values, and should integrate robust data from systematic research. As a consequence, clinical research has become more complex and methods have become more rigorous, and evidence is usually not easily translated into clinical practice. Therefore, the instruction of clinical research methods for scientists and clinicians must adapt to this new reality. To address this challenge, a global distance-learning clinical research-training program was developed, based on collaborative learning, the pedagogical goal of which was to develop critical thinking skills in clinical research. We describe and analyze the challenges and possible solutions of this course after 5 years of experience (2008–2012) with this program. Through evaluation by students and faculty, we identified and reviewed the following challenges of our program: 1) student engagement and motivation, 2) impact of heterogeneous audience on learning, 3) learning in large groups, 4) enhancing group learning, 5) enhancing social presence, 6) dropouts, 7) quality control, and 8) course management. We discuss these issues and potential alternatives with regard to our research and background.Item A medical student-delivered smoking prevention program, education against tobacco, for secondary schools in Brazil : study protocol for a randomized trial.(2017) Xavier, Luiz Eduardo de Freitas; Souza, Breno Bernardes; Lisboa, Oscar Campos; Seeger, Werner; Groneberg, David Alexander; Tran, Thien-An; Fries, Fabian Norbert; Corrêa, Paulo César Rodrigues Pinto; Brinker, Titus JosefBackground: Smoking is the largest preventable cause of morbidity and mortality in Brazil. Education Against Tobacco (EAT) is a large network of medical students in 13 countries who volunteer for school-based prevention in the classroom setting. A recent quasi-experimental EAT study conducted in Germany showed significant short-term smoking cessation effects on 11- to 15-year-old adolescents. Objective: The aim of this study is both to describe and to provide the first randomized long-term evaluation of the EAT intervention involving a photoaging app for its effectiveness to reduce the smoking prevalence among 12- to 17-year-old pupils in Brazilian public schools. Methods: A randomized controlled trial will be conducted among approximately 1500 adolescents aged 12 to 17 years in grades 7-11 of public secondary schools in Brazil. The prospective experimental study design includes measurements at baseline and at 6 and 12 months postintervention. The study groups will consist of randomized classes receiving the standardized EAT intervention (90 minutes of mentoring in a classroom setting) and control classes within the same schools (no intervention). The questionnaire measures smoking status, gender, social, and cultural aspects as well as predictors of smoking. Biochemical validation of smoking status is conducted via random carbon monoxide measurements. The primary end point is the difference of the change in smoking prevalence in the intervention group versus the difference in the control group at 12 months of follow-up. The differences in smoking behavior (smoking onset, quitting) between the 2 groups as well as effects on the different genders will be studied as secondary outcomes. Results: The recruitment of schools, participating adolescents, and medical students was conducted from August 2016 until January 2017. The planned period of data collection is February 2017 until June 2018. Data analysis will follow in July 2018 and data presentation/publication will follow shortly thereafter. Conclusions: This is the first evaluative study of a medical student–delivered tobacco prevention program in Brazil and the first randomized trial on the long-term effectiveness of a school-based medical student–delivered tobacco prevention program in general.Item No controversy : e-cigarettes are not a treatment for tobacco/nicotine cessation.(2022) Corrêa, Paulo César Rodrigues PintoItem On the case report of Platypnea-orthodeoxia after SARSCoV-2 pneumonia plus historical notes.(2020) Corrêa, Paulo César Rodrigues PintoItem Response to Giovanni Battista Morgagni and the Foundation of Modem Medicine.(2016) Vale, Flávia F. A.; Corrêa, Paulo César Rodrigues PintoItem A smoking prevention program delivered by medical students to secondary schools in Brazil called “Education Against Tobacco” : randomized controlled trial.(2019) Lisboa, Oscar Campos; Souza, Breno Bernardes; Xavier, Luiz Eduardo de Freitas; Almeida, Matheus Rocha; Corrêa, Paulo César Rodrigues Pinto; Brinker, Titus JosefBackground: Smoking is the largest preventable cause of mortality in Brazil. Education Against Tobacco (EAT) is a network of more than 3500 medical students and physicians across 14 countries who volunteer for school-based smoking prevention programs. EAT educates 50,000 adolescents per year in the classroom setting. A recent quasi-experimental study conducted in Germany showed that EAT had significant short-term smoking cessation effects among adolescents aged 11 to 15 years. Objective: The aim is to measure the long-term effectiveness of the most recent version of the EAT curriculum in Brazil. Methods: A randomized controlled trial was conducted among 2348 adolescents aged 12 to 21 years (grades 7-11) at public secondary schools in Brazil. The prospective experimental design included measurements at baseline and at 6 and 12 months postintervention. The study groups comprised randomized classes receiving the standardized EAT intervention (90 minutes of mentoring in a classroom setting) and control classes in the same schools (no intervention). Data were collected on smoking status, gender, social aspects, and predictors of smoking. The primary endpoint was the difference in the change in smoking prevalence between the intervention group and the control group at 12-month follow-up. Results: From baseline to 12 months, the smoking prevalence increased from 11.0% to 20.9% in the control group and from 14.1% to 15.6% in the intervention group. This difference was statistically significant (P<.01). The effects were smaller for females (control 12.4% to 18.8% vs intervention 13.1% to 14.6%) than for males (control 9.1% to 23.6% vs intervention 15.3% to 16.8%). Increased quitting rates and prevented onset were responsible for the intervention effects. The differences in change in smoking prevalence from baseline to 12 months between the intervention and control groups were increased in students with low school performance. Conclusions: To our knowledge, this is the first randomized trial on school-based tobacco prevention in Brazil that shows significant long-term favorable effects. The EAT program encourages quitting and prevents smoking onset, especially among males and students with low educational background.Item The public health impact of e-cigarette use : revisiting Geoffrey Rose’s prevention strategies.(2023) Ravara, Sofia Belo; Corrêa, Paulo César Rodrigues Pinto; Calheiros, Jose Manuel Lage Campelo; Pisinger, CharlottaItem Update on the approach to smoking in patients with respiratory diseases.(2019) Sales, Maria Penha Uchoa; Araújo, Alberto José de; Chatkin, José Miguel; Godoy, Irma de; Pereira, Luiz Fernando Ferreira; Castellano, Maria Vera Cruz de Oliveira; Minamoto, Suzana Erico Tanni; Almeida, Adriana Ávila de; Chatkin, Gustavo; Silva, Luiz Carlos Côrrea da Silva; Gonçalves, Cristina Maria Cantarino; Botelho, Clóvis; Santos, Ubiratan Paula; Viegas, Carlos Alberto de Assis; Sestelo, Maristela Rodrigues; Meireles, Ricardo Henrique Sampaio; Corrêa, Paulo César Rodrigues Pinto; Oliveira, Maria Eunice Moraes de; Reichert, Jonatas; Lima, Mariana Silva; Silva, Celso Antonio Rodrigues daSmoking is the leading cause of respiratory disease (RD). The harmful effects of smoking on the respiratory system begin in utero and influence immune responses throughout childhood and adult life. In comparison with “healthy” smokers, smokers with RD have peculiarities that can impede smoking cessation, such as a higher level of nicotine dependence; nicotine withdrawal; higher levels of exhaled carbon monoxide; low motivation and low self-efficacy; greater concern about weight gain; and a high prevalence of anxiety and depression. In addition, they require more intensive, prolonged treatment. It is always necessary to educate such individuals about the fact that quitting smoking is the only measure that will reduce the progression of RD and improve their quality of life, regardless of the duration and severity of the disease. Physicians should always offer smoking cessation treatment. Outpatient or inpatient smoking cessation treatment should be multidisciplinary, based on behavioral interventions and pharmacotherapy. It will thus be more effective and cost-effective, doubling the chances of success.