Navegando por Autor "Cesarino Filho, Gracco"
Agora exibindo 1 - 2 de 2
Resultados por página
Opções de Ordenação
Item Fatal spotted fever rickettsiosis, Minas Gerais, Brazil.(2003) Galvão, Márcio Antônio Moreira; Dumler, J. Stephen; Mafra, Cláudio Lísias; Calic, Simone Berger; Chamone, Chequer Buffe; Cesarino Filho, Gracco; Olano, Juan Pablo; Walker, David HughesThe emergence and reemergence of a serious infectious disease are often associated with a high case-fatality rate because of misdiagnosis and inappropriate or delayed treatment. The current reemergence of spotted fever rickettsiosis caused by Rickettsia rickettsii in Brazil has resulted in a high proportion of fatal cases. We describe two familial clusters of Brazilian spotted fever in the state of Minas Gerais, involving six children 9 months to 15 years of age; five died. Immunohistochemical investigation of tissues obtained at necropsy of a child in each location, Novo Cruzeiro and Coronel Fabriciano municipalities, established the diagnosis by demonstration of disseminated endothelial infection with spotted fever group rickettsiae. The diagnosis in the two fatal cases from Coronel Fabriciano and the surviving patient from Novo Cruzeiro was further supported by immunofluorescence serologic tests.Item Spotted fever rickettsiosis in Coronel Fabriciano, Minas Gerais State.(2003) Galvão, Márcio Antônio Moreira; Calic, Simone Berger; Chamone, Chequer Buffe; Siqueira, Cláudio Lísias Mafra de; Cesarino Filho, Gracco; Olano, Juan Pablo; Walker, David HughesWe report cases of spotted fever rickettsiosis in Coronel Fabriciano Municipality of Minas Gerais State, Brazil. The cases occurred in May and June of 2000. During this period there were two deaths among children from an area named Pedreira in a periurban area of this municipality. In a boy who died with clinical manifestations of Brazilian spotted fever, a necropsy revealed the presence of a spotted fever group Rickettsia. The serological results confirm the difficulty in the differential diagnosis of patients with symptoms of rickettsial diseases.