Navegando por Autor "Abad, Anis Charkhi Sahl"

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Effect of purslane seed supplementation on inflammatory cytokines, oxidative stress and muscle damage in response to high‑intensity intermittent exercise in national athlete runners.
(2019) Zare, Mohammad Mehdi; Ghram, Amine; Akbarnejad, Ali; Soori, Rahman; Abad, Anis Charkhi Sahl; Ghuchan, Fatemeh Azizi; Silva, Albená Nunes da
Background Purslane supplementation has anti-oxidative, anti-inflammatory, skeletal muscle-relaxant activities. However, it is unknown if the ingestion of purslane will affect the oxidative stress and cytokines in exercise-induced muscle damage. The aim of the present study was to examine the effect of purslane supplementation after high-intensity interval exercise (HIIE) on oxidative stress, cytokines, and muscle damage level in young athlete male runners. Methods Seven healthy young male runners performed 2.5 km HIIE treadmill protocol. Athletes repeated this protocol following 10 days of purslane seed supplementation (1000 mg/day). Blood samples were collected at baseline and following HIIE protocol and analyzed for oxidative stress (9-HODE and 13-HODE), cytokines (IL-17, and TNF-α), and muscle damage (LDH) biomarkers. Results At baseline and following HIIE protocol, 9-HODE, 13-HODE, IL-17, TNF-α, LDH levels were significantly (p < 0.001) lower after purslane supplementation in compared to before purslane supplementation. HIIE protocol induced a significant increase in 9-HODE, 13-HODE, IL-17, TNF-α, and LDH before and after purslane supplementation. Conclusion Purslane seed supplementation was able to reduce oxidative stress (9-HODE, 13-HODE), proinflammatory cytokines (IL-17 and TNF-α), and muscle damage (LDH) in male runners after HIIE performance compared to baseline levels. After 10 days of supplementation, the levels were reduced compared to levels pre-supplementation but not after HIIE supplementation in supplemented athletes.